LIQUID SPECIAL
BLOW-FILL-SEAL

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USING ONE MACHINE FOR THREE PRODUCTION STEPS

A blow-fill-seal (BFS) machine minimizes contamination risk and reduces production costs.

Reducing machine interfaces is a key factor in getting three steps from one machine only. Integrated blow-fill-seal technology combines:

  • Forming
  • Sterile/aseptic filling
  • Closing

Rieckermann knows the integral parts in a pharmaceutical filling process and how to manage their interfaces. We are a reliable partner and have the experience necessary to set up your industrial solution for dedicated pharmaceutical applications.

GET IN TOUCH

Mrs. Katrin Winter
Team Assistant, Pharmaceutical Industry
Email: [email protected]

Process, qualification & GMP

  • Elimination of cross contamination risk in your filling process is the right GMP mindset
  • Large batch production without direct human interference
  • Significant reduction of qualification & validation efforts
  • Fewer SOPs for easy control of your facility
  • High degree of sterility assurance backed up by scientific research

Investment, operation & marketing

  • Smaller plant facility layout
    • Less equipment
    • Less storage of raw materials & consumables
    • Fewer operational costs for clean rooms, machine maintenance, manpower, etc.
  • Significantly lower costs per container compared to other liquid filling processes
  • Automated CIP / SIP processes
  • Flexible container design
  • Improved functionality of finished product, with
    • No glass breakage
    • No refill of inhalers

LIQUID SPECIAL
BLOW-FILL-SEAL VIDEO & IMAGE

BLOW-FILL-SEAL PROCESS

Thermoplastic resin is extruded into a tubular shape (parison) which is continuously flushed with sterile air.

The bottom of the parison is pinched and closed, while the top is held open with the help of the special mold design. At the proper length, the mold is closed and the parison is cut. The parison in the mold is then conveyed to the point of fill.

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